Bethesda House provides space on-site for a variety of partner agencies that have satellite programs at Bethesda House. Partners include: Alliance for Positive Health, Schenectady County Health Dept., Cornell Cooperative Extension, the YWCA, CDPHP Insurance, Fidelis Insurance, and the Legal Aid Society of NENY.

Bethesda House participates in the Regional Homeless Management Information System, the Homeless Services Planning Board, the Schenectady County Ten-Year Plan to End Homelessness, the Evictions Task Force, the County Food Providers, Adults at Risk Committee, and Schenectady Coalition for a Healthy Community.

The following is a list of partnerships:

The Alliance for Positive Health
Catholic Charities AIDS Services
Healthy Schenectady Families
Legal Aid Society of NENY
New Choices Recovery Center
Office of Fair Housing
SAFE Inc. of Schenectady
Schenectady County DSS
Schenectady Community Action Program (SCAP)
Schenectady Home Town Health Center
Schenectady Municipal Housing Authority (SMHA)
Sexual Assault Support Services of PPMH
The YMCA of Schenectady
Ellis Hospital Department of Psychiatry
Ellis Hospital: Care Central
The YWCA of Schenectady
Schenectady County Re-entry Task Force
Cornell University Cooperative Extension
The City Mission
Peter Young: Housing, Industry & Treatment
County Waste & Recycling